JRF Position in Bioinformatics - Molecular Dynamics Simulations | 26 Feb, 2019

Project Title

Investigating the effect of Osmolytes on the Interplay of Dynamics of Water, protein and DNA: Implications for Modulating Protein-DNA Specificity

Funding Agency

Department of Biotechnology, Government of India


As per rules and regulations

Essential qualification

First class in M. Sc. or M. Tech. (Biophysics, Bioinformatics, Biotechnology, Physics, or related fields)

Project Description

Specificity in the binding of proteins to DNA is important for the tight regulation of various cellular processes including replication, transcription etc. Loss of protein-DNA specificity has adverse ramifications including uncontrolled cell proliferation (cancer) etc. Osmolytes are commonly known to be expressed under stress conditions. This project aims to delineate the effect of osmolytes on protein-DNA specificity using computational methods (molecular dynamics simulations).


Interested candidates may send their latest resume by email to Dr. Vigneshwar Ramakrishnan (This email address is being protected from spambots. You need JavaScript enabled to view it.) on or before 26 February 2019. Shortlisted candidates will have to appear for a test and interview. The date of the test and interview will be notified by email only to the shortlisted candidates. No TA/DA will be paid for appearing in the interview.