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Sl. No
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Course content
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Duration (in hours)
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Module
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1.
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Introduction to tissue engineering, Cells as therapeutic Agents with examples, Cell numbers and growth rates.
|
2
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Module 1
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|
2.
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Tissue organization, Tissue Components, Tissue types, Functional subunits. Tissue Dynamics, Dynamic states of tissues, Homeostasis in highly prolific tissues and Tissue repair. Angiogenesis.
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3
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Module 2 |
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3.
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Cellular fate processes, Cell differentiation, Cell migration - underlying biochemical process.
|
3
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Module 3 |
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4.
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Cell division - mitotic cell cycle, Cell death - biological description of apoptosis.
|
3
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Module 4 |
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5.
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Coordination of cellular fate processes - soluble signals, types of growth factors and chemokines, sending and receiving a signal, processing a signal, integrated responses, soluble growth factor receptors, Malfunctions in soluble signaling.
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3
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Module 5 |
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6.
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Cell-extracellular matrix interactions - Binding to the ECM, Modifying the ECM, Malfunctions in ECM signaling.
Direct Cell-Cell contact - Cell junctions in tissues, malfunctions in direct cell-cell contact signaling. Response to mechanical stimuli. |
3
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Module 6 |
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7.
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Measurement of cell characteristics - cell morphology, cell number and viability, cell-fate processes, cell motility, cell function.
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2
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Module 7 |
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8.
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Cell and tissue culture - types of tissue culture, media, culture environment and maintenance of cells in vitro, cryopreservation.
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3
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Module 8 |
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9.
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Basis for Cell Separation, characterization of cell separation, methods of cell separation.
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3
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Module 9 |
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10.
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Biomaterials in tissue engineering - biodegradable polymers and polymer scaffold processing.
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3
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Module 10 |
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11.
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Growth factor delivery, Stem cells.
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3
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Module 11 |
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12.
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Gene therapy.
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1
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Module 12 |
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13.
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Bioreactors for Tissue Engineering.
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1
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Module 13 |
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14.
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In vivo cell & tissue engineering case studies: Artificial skin, Artificial blood vessels.
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3
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Module 14 |
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15.
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In vivo cell & tissue engineering case studies: Artificial pancreas, Artificial liver.
|
3
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Module 15 |
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16.
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In vivo cell & tissue engineering case studies: Regeneration of bone, muscle.
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3
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Module 16 |
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17.
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In vivo cell & tissue engineering case studies: Nerve regeneration.
|
3
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Module 17 |
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Total
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45
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