school and education

Vascular Biology Lab Workshops read more

Publications

[tab_grid]
[column size="8-10"] [tab_content content_id="tabs_example1"]
    • Sriram Ravindran, Gino A Kurian (2018). Effect of sodium thiosulfate postconditioning on ischemia-reperfusion injury induced mitochondrial dysfunction in rat heart. Journal of Cardiovascular Translational Research. (Article in press)
    • Sriram Ravindran, Gino A Kurian (2018). Cardiac mitochondria play key role in the cardioprotection mediated by sodium thiosulfate preconditioning. Revista Espanola de Cardiologia. (Article in Press)
    • A. Mahalakshmi, Gino A. Kurian (2018). Evaluating the impact of diabetes and diabetic cardiomyopathy rat heart on the outcome of ischemia-reperfusion associated oxidative stress. Free Radical Biology and Medicine. Pages 35-43.
    • Ravindran, S., Ramachandran, K., Kurian, G.A., (2018). Sodium Thiosulfate Mediated Cardioprotection Against Myocardial Ischemia-Reperfusion Injury Is Defunct In Rat Heart With Co-Morbidity Of Vascular Calcification. Biochimie. Apr;147:80-88.
    • Mahalakshmi, A., Kurian, G.A., (2018). Evaluating the effect of green synthesized copper oxide nanoparticles on oxidative stress and mitochondrial function using murine model. IET Nanobiotechnology (Accepted in press)
    • Shanmugam, K., Ravindran, S., Kurian, G.A., Rajesh, M., (2018). Fisetin confers cardioprotection against myocardial ischemia reperfusion injury by suppressing mitochondrial oxidative stress, mitochondrial dysfunction and inhibiting glycogen synthase kinase - 3β activity. Oxidative Medicine and Cellular Longevity, vol. 2018, Article ID 9173436, 16 pages
    • Boovarahan, S.R., Kurian, G.A., (2018). Mitochondrial dysfunction: a key player in the pathogenesis of cardiovascular diseases linked to air pollution. . Reviews on Environmental Health, doi:10.1515/reveh-2017-0025
    • Nandi, S., Ravindran, S., Kurian, G.A., (2018). Role of endogenous hydrogen sulfide in cardiac mitochondrial preservation during ischemia reperfusion injury. Biomedicine & pharmacotherapy.97, 271-279.
    • Ansari, M., Kurian, G.A., (2017). Differential effect of aqueous Desmodium gangeticum root extract mediated TiO2 nanoparticles on isolated mitochondria, cells and Wistar rats. Asian Pacific Journal of Tropical Biomedicine 7 (11), 1031-1035
    • Mohan, D., Balasubramanian, E.D., Ravindran, S., Kurian, G.A., (2017). Renal mitochondria can withstand hypoxic/ischemic injury secondary to renal failure in uremic rats pretreated with sodium thiosulfate. Indian journal of pharmacology 49, 317-321
    • Ramani, R., Ramachandran, A., Ravindran, S., Kurian, G.A., (2017). Erythrocyte Membrane Bound ATPase and Antioxidant Enzyme Changes Associated with Vascular Calcification is Reduced by Sodium Thiosulfate. Indian journal of clinical biochemistry : IJCB 32, 487-492.
    • Ravindran, S., Boovarahan, S.R., Shanmugam, K., Vedarathinam, R.C., Kurian, G.A., (2017). Sodium Thiosulfate Preconditioning Ameliorates Ischemia/Reperfusion Injury in Rat Hearts Via Reduction of Oxidative Stress and Apoptosis. Cardiovascular drugs and therapy 31, 511-524.
    • Ravindran, S., Jahir Hussain, S., Boovarahan, S.R., Kurian, G.A., (2017). Sodium thiosulfate post-conditioning protects rat hearts against ischemia reperfusion injury via reduction of apoptosis and oxidative stress. Chemico-biological interactions 274, 24-34.
    • Ravindran, S., Swaminathan, K., Ramesh, A., Kurian, G.A., (2017). Nicorandil attenuates neuronal mitochondrial dysfunction and oxidative stress associated with murine model of vascular calcification. Acta neurobiologiae experimentalis 77, 57-67.
    • Ravindran, S. and G. A. Kurian (2017). The role of secretory phospholipases as therapeutic targets for the treatment of myocardial ischemia reperfusion injury. Biomed Pharmacother 92: 7-16.
    • Ravindran, S., et al. (2017). Vascular calcification abrogates the nicorandil mediated cardio-protection in ischemia reperfusion injury of rat heart. Vascul Pharmacol 89: 31-38.
    • Vasanth, S. B. and G. A. Kurian (2017). Toxicity evaluation of silver nanoparticles synthesized by chemical and green route in different experimental models. Artif Cells Nanomed Biotechnol: 1-7.
    • Ansari, S. B. and G. A. Kurian (2016). Hydrogen sulfide modulates sub-cellular susceptibility to oxidative stress induced by myocardial ischemic reperfusion injury. Chem Biol Interact 252: 28-35.
    • Ayswarya, A. and G. A. Kurian (2016). Sensitivity of Interfibrillar and Subsarcolemmal Mitochondria to Cobalt Chloride-induced Oxidative Stress and Hydrogen Sulfide Treatment. Indian J Pharm Sci 78(1): 151-158.
    • Banu, S. A., et al. (2016). Hydrogen sulfide post-conditioning preserves interfibrillar mitochondria of rat heart during ischemia reperfusion injury. Cell Stress Chaperones 21(4): 571-582.
    • Krishnaraj, P., et al. (2016). The renal mitochondrial dysfunction in patients with vascular calcification is prevented by sodium thiosulfate. Int Urol Nephrol 48(11): 1927-1935.
    • Kurian, G. A. (2016). Hypoglycemic effect of poly-herbal combination in streptozotocin-induced diabetic rats. 2016 11(2): 8.
    • Kurian, G. A., et al. (2016). The Role of Oxidative Stress in Myocardial Ischemia and Reperfusion Injury and Remodeling: Revisited. Oxid Med Cell Longev 2016: 1656450.
    • N. Hari, S. A., Gino A. Kurian, R. Rajmohan and R. Ravikumar (2016). Green Synthesis, characterization of novel 1,2,3-triazole-chalcone hybrids and evaluation of their antibacterial, antifungal and antiproliferation activity. Der Pharmacia Lettre 8(19): 80.
    • Ramani, R., et al. (2016). Erythrocyte Membrane Bound ATPase and Antioxidant Enzyme Changes Associated with Vascular Calcification is Reduced by Sodium Thiosulfate. Indian Journal of Clinical Biochemistry: 1-6.
    • Ravindran, S., et al. (2016). Hydrogen sulfide preconditioning shows differential protection towards interfibrillar and subsarcolemmal mitochondria from isolated rat heart subjected to revascularization injury. Cardiovasc Pathol 25(4): 306-315.
    • Shakila Banu, N. S., Nasreen Fathima, M. Chandni and Gino. A. Kurian (2016). Effect of Sodium Thiosulfate on Isolated Cardiacinterfibrillar and Subsarcolemmal Mitochondria. Indian J Pharm Sci 78(5): 10.
    • Baldev, N., et al. (2015). Effect of mitochondrial potassium channel on the renal protection mediated by sodium thiosulfate against ethylene glycol induced nephrolithiasis in rat model. Int Braz J Urol 41(6): 1116-1125.
    • Subhash, N., et al. (2015). Sodium thiosulfate protects brain in rat model of adenine induced vascular calcification. Neurochem Int 90: 193-203.
    • Vaitheeswari, S., et al. (2015). Studying inhibition of calcium oxalate stone formation: an in vitro approach for screening hydrogen sulfide and its metabolites. Int Braz J Urol 41(3): 503-510.
    • Jamuna, K. S.; Banu, Shakila; Brindha, P.; Kurian, G.A. Nano-scale preparation of Titanium dioxide by Desmodium gangeticum root aqueous extract. Ceramics International. 2014. 11933-11940.
    • Sudhasree, S.; Shakila Banu, A.; Brindha, P.; Kurian, G.A. Comparative evaluation of nickel nanoparticles synthesized by chemical and green route for the biological effect and toxicity. Toxicological and Environmental Chemistry. 2014. 1-12.
    • Kurian, G.A., Manjusha, Nair, S.S., Varghese, T., Padikkala, J. Short-term effect of G-400, poly herbal formulation in the management of hyperglycemia and hyperlipidemia conditions in type 2 diabetes mellitus patients. Nutrition (Burbank, Los Angeles County, Calif.). 2014.
    • Kurian, G.A., Berenshtein, E., Kakhlon, O., Chevion, M. Energy status determines the distinct biochemical and physiological behavior of interfibrillar and sub-sarcolemmal mitochondria. Biochemical and biophysical research communications. 2012, 428, 376-82.
    • Kurian, G.A., Berenshtein, E., Saada, A., Chevion, M. Rat cardiac mitochondrial sub-populations show distinct features of oxidative phosphorylation during ischemia, reperfusion and ischemic preconditioning. Cellular physiology and biochemistry. International journal of experimental cellular physiology, biochemistry, and pharmacology. 2012, 30, 83-94.
    • Kurian, G.A., Paddikkala, J. Methanol extract of Desmodium gangeticum DC root mimetic post-conditioning effect in isolated perfused rat heart by stimulating muscarinic receptors. Asian Pac J Trop Med. 2012, 5, 448-54.
    • Srivats, S., Ramakrishnan, G., Paddikkala, J., Kurian, G.A. An in vivo and in vitro analysis of free radical scavenging potential possessed by Desmodium gangeticum chloroform root extract: interpretation by gsms. Pakistan journal of pharmaceutical sciences. 2012, 25, 27-34.
    • Kurian, G., Seetharaman, A., Subramanian, N., Paddikkala, J. A Novel Approach for Oral Delivery of Insulin via Desmodium gangeticum Aqueous Root Extract. J Young Pharm. 2010, 2, 156-61.
    • Kurian, G.A., Paddikkala, J. N-acetylcysteine and magnesium improve biochemical abnormalities associated with myocardial ischaemic reperfusion in South Indian patients undergoing coronary artery bypass grafting: a comparative analysis. Singapore medical journal. 2010, 51, 381-8.
    • Kurian, G.A., Paddikkala, J. Oral delivery of insulin with Desmodium gangeticum root aqueous extract protects rat hearts against ischemia reperfusion injury in streptozotocin induced diabetic rats. Asian Pacific Journal of Tropical Medicine. 2010, 3, 94-100.
    • Kurian, G.A., Suryanarayanan, S., Raman, A., Padikkala, J. Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. Chin Med. 2010, 5, 3.
    • Kurian, G.A., Padikkala, J. Biochemical changes in liver and kidney functions of patients subjected to revascularization in CABG procedure: Role of magnesium supplementation. Applied Cardiopulmonary Pathophysiology 14: 29-39, 2010.
    • Kurian, G.A., R.S.S. Srivats, R. Gomathi, M.M. Shabi and J. Paddikkala. Interpretation of Inotropic Effect Exhibited by Desmodium gangeticum Chloroform Root Extract Through GSMS and Atomic Mass Spectroscopy: Evaluation of its Anti Ischemia Reperfusion Property in Isolated Rat Heart. Asian Journal of Biochemistry Volume 5, Number 1, 23-32, 2010.
    • Kurian, GA.,Shabi MM, Padikkala J. Cardiotonic and anti ischemic reperfusion injury effect of Desmodium gangeticum root methanol extract. Turkish Journal of Biochemistry. 2010,35(2),81-88.
    • Kurian, G.A., Padikkala J. Cardioprotective effect of aqueous extract of the Desmodium Gangeticum DC (L) root in isolated rat heart against ischemic reperfusion injury :role of mitochondrial enzymes and sarcoplasmic atpase: (adjudged as the best paper in the field of Pharmacology). Indian Journal of Pharmaceutical Science. 2010, 72 (6) 745-752.
    • Siddharselvam G, Saranya V, Veena K, Sudhan P, Swaminathan S, Kurian, G.A. Effect of poly herbal formulation on streptozotocin- induces diabetic rat. Journal of Pharmacy Research. 2010; 3(2).
    • Kurian, G.A., AV Seetharaman, NR Subramanian, J Paddikkala. Desmodium Gangeticum Aqueous Root Extract Mixed Insulin, An Alternate Oral Route Delivery Of Insulin In Normal And Streptozotocin Induced Diabetic Rats. Journal of young Pharmacist. 2010;2(2), 156-161 .
    • Kurian, G.A., Rajamani T,Ramanarayanan P, Padikkala J. A comparative study on in-vitro and in-vivo antioxidant activities of aqueous extract of Desmodium gangeticum DC (Leguminosae) root. International journal of Green pharmacy. 2009; 3(4): 324-331.
    • Kurian, G.A., Gandhi Siddhar Selvam, Vidyasagar Saranya. Oral administration of insulin mixed desmodium gangeticum root aqueous extract reduces oxidative stress mediated by myocardial ischemia reperfusion in isolated rat hearts. Journal of pharmacy research. 2009; 2(6): 1013-1018.
    • Kurian. G.A., Paddikkala J. Administration of aqueous extract of Desmodium gangeticum DC root protects the rat heart against oxidative stress induced by ischemic reperfusion injury. Indian Journal of Experimental Biology. 2009; 47: 129-135.
    • Kurian, G.A., Phil, M., Paddikkala, J. Antioxidant status of South Indian patients undergoing coronary artery bypass graft surgery: a role of intra operative magnesium supplementation. International journal of cardiology. 2008, 128, 139-41.
    • Kurian, G.A., Yagnesh, N., Kishan, R.S., Paddikkala, J. Methanol extract of Desmodium gangeticum roots preserves mitochondrial respiratory enzymes, protecting rat heart against oxidative stress induced by reperfusion injury. J Pharm Pharmacol. 2008, 60, 523-30.
    • Kurian, G.A., Paddikkala J. Effect of Intra-Operative Magnesium Supplementation in Plasma Antioxidant Levels, Trace Elements and Electrolyte Balance in Serum of Coronary Artery Bypass Graft Patients. Journal of Clinical and Basic Cardiology. 2007; 10 (1-4): 11-15.
    • Kurian, G.A., Paddikkala J. The Effect of Verapamil Administred before the Reperfusion Insult in Isolated Preconditioned Rat Heart on the Microsomal ATPase and Mitochondrial Enzyme Activities. Iranian Journal of Medical Sciences. 2007; 32(4).
    • Kurian, G.A., Murugan M, Padikkala J. Effect of magnesium in modulating the activity of Na+ K+ ATPase, Ca2+ ATPase, Mg2+ ATPase and 5’ nucleotidase in South Indian patients undergoing coronary artery bypass graft surgery. Journal of Clinical and Basic Cardiology. 2006; 9 (Issue 1-4), 10-16.
  • Kurian, G.A., Philip, S., Varghese, T. Effect of aqueous extract of the Desmodium gangeticum DC root in the severity of myocardial infarction. J Ethnopharmacol. 2005, 97, 457-61.
    • [/tab_content] [/column] [/tab_grid]